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By 12 weeks, 69% of the patients in the minimal counseling group had 8 consecutive weeks of illicit opiate or cocaine use or three emergency situations compared with 41% of those receiving standard counseling and 19% of those receiving enhanced services.

Dosage is based on your medical condition and response to therapy.

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Cigarette smoking during adolescence is a risk factor for the development of substance abuse in adulthood.

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Patients with significant opioid dependence may require a starting dose of 30 to 40mg per day; this dose range should be adequate for even the most severe withdrawal.

The authors concluded that the “safety switch” or the mechanisms existing in the body to prevent harmful effects are overridden by the drug administration (Roelands et al.

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